Product ID:HYGROMYCIN B, 400051
MSDS Date:04/02/1999
FSC:6505
NIIN:00N092489
Status Code:A
MSDS Number: CJTCK

Emergency Phone: (800)424-9300

Info Phone: 800-854-3417

Cage: 29089

Telephone: 619-450-5558; 800-854-3417

Cage: 29089

HYGROMYCIN B

CAS: 31282-04-9

RTECS: WK2130000

LD50 LC50 Mixture:SEE TOXICOLOGICAL INFO
Routes of Entry: Inhalation:YES Skin:YES Ingestion:YES
Reports of Carcinogenicity:NTP:NO IARC:NO OSHA:NO
Health Hazards Acute and Chronic:ACUTE EFFECTS: MAY BE HARMFUL BY
INTESTION, INHALATION OR ABSORPTION THROUGH SKIN. MATERIAL MAY
CAUSE IRRITATION TO THE EYES, SKIN, MUCOUS MEMBRANES AND THE UPPER
RESPIRATORY TRACT. EXPOSURE TO MATERI AL MAY CAUSE SEVERE AND
PERMANENT DAMAGE TO THE EYES AND MODERATE IRRITATION TO THE SKIN.
CHRONIC EFFECTS: STUDIES WITH LABORATORY ANIMALS HAVE SHOWN THAT
LONG-TERM EXPOSURE TO HYGROMYCIN B MAY CAUSE HEARING LOSS AND/OR
CATARACTS.
Effects of Overexposure:SEE HEALTH HAZARDS.

First Aid:SKIN: IN CASES OF SKIN CONTACT, WASH IMMED W/COPIOUS AMOUNTS
OF WATER FOR AT LEAST 15 MINUTES. REMOVE CONTAMINATED CLOTHING AND
SHOES AND WASH BEFORE WEARING. CONSULT A MD. EYES: IN CASES OF EYE
CONTA CT, FLUSH IMMED W/COPIOUS AMOUNTS OF WATER FOR AT LEAST 15
MINUTES. ASSURE ADEQUATE FLUSHING BY SEPARATING EYELIDS W/FINGERS.
CONSULT A MD. INHAL: IN CASES OF INHALATION, REMOVE TO FRESH AIR
AND MONIT OR BREATHING. IF BREATHING BECOMES DIFFICULT, GIVE OXYGEN
AND CONSULT A MD. IF BREATHING STOPS, GIVE ARTIFICIAL RESPIRATION
AND CONSULT A MD. INGEST: IN CASE OF INGESTION, WASH MOUTH OUT
W/WATER AND C ONSULT LOCAL POISON CENTER AND A MD.

Extinguishing Media:DRY CHEMICAL POWDER, CARBON DIOXIDE, WATER SPRAY,
ALCOHOL OR POLYMER FOAM.
Fire Fighting Procedures:USE NIOSH APPROVED SCBA AND FULL PROTECTIVE
EQUIPMENT TO PREVENT CONTACT WITH SKIN AND EYES.
Unusual Fire/Explosion Hazard:UPON THERMAL DECOMPOSITION, IT MAY EMIT
TOXIC GASES.

Spill Release Procedures:EVACUATE AREA. WEAR A NIOSH APPROVED
RESPIRATOR, CHEMICAL SAFETY GOGGLES, RUBBER BOOTS AND HEAVY RUBBER
GLOVES. SWEEP UP AND PLACE IN A SUITABLE CONTAINER. AVOID RAISING
DUST. HOLD FOR APPROPRIATE DIS POSAL. WASH SPILL SITE AND VENTILATE
AREA AFTER MATERIAL PICKUP IS COMPLETE.

Handling and Storage Precautions:STORE IN A TIGHTLY CLOSED CONTAINER IN
A +4C REFRIGERATOR. MATERIAL IS AN IRRITANT. AVOID CONTACT WITH
MATERIAL. AVOID PROLONGED OR REPEATED EXPOSURE. LAB SHOULD BE
EQUIPPED WITH A SAFETY SHOWER AND A N EYE WASH STATION. WASH
THOROUGHLY AFTER HANDLING MATERIAL.

Respiratory Protection:USE A NIOSH APPROVED RESPIRATOR.
Ventilation:HANDLE IN A CHEMICAL FUME HOOD WITH ADEQUATE VENTILATION.
Protective Gloves:CHEMICAL RESISTANT GLOVES.
Eye Protection:ANSI APPROVED CHEMICAL WORKERS GOGGLES .
Other Protective Equipment:ANSI APPROVED EYE WASH AND DELUGE SHOWER .
WEAR SUITABLE PROTECTIVE CLOTHING.
Supplemental Safety and Health
HYGROMYCIN B - MOLECULAR WEIGHT: 527.5; MOLECULAR FORMULA:
C*2OH*37N*3O*13.

Appearance and Odor:LIQUID. SUPPLIED AS AN AQUEOUS SOLUTION.

N/A.
Stability Condition to Avoid:N/A. STABLE UNDER NORMAL HANDLING
PROCEDURES.
Hazardous Decomposition Products:UPON THERMAL DECOMPOSITION, MAY EMIT
TOXIC GASES INCLUDING CARBON MONOXIDE, CARBON DIOXIDE, AND NITROGEN
OXIDES.

Waste Disposal Methods:COUNTRY, FEDERAL, STATE AND LOCAL REGULATIONS
ARE VARIED AND CHANGE FREQUENTLY. FOR THIS REASON, WE RECOMMEND
THAT YOU CONTACT YOUR LOCAL DEPARTMENT OF HEALTH SERVICES FOR
INFORMATION ON THE DISPOSAL OF THIS PRODUCT OR ARRANGE FOR
DISPOSAL BY A LICENSED DISPOSAL COMPANY.

Toxicological Information:RTECS NUMBER: WK2130000. TOXICITY DATA AND
REFERENCES: IHL; RAT; LC50: 2220 ?G/M3/4H CONJUNCTIVE IRRITATION;
AGGRESSION 1973. GIGIENA I SANITARIYA. FOR ENGLISH TRANSLATION, SEE
HYSAAV. 38(5), 11. ORL; MUS; LD50: 46000 UNITS/KG 1967.
PHARMACEUTICAL CHEMISTRY JOURNAL (ENGLISH TRANSLATION). TRANSLATION
OF KHFZAN. 1, 396. IPR; RAT; LD50: 63 MG/KG 1973. GIGIENA I
SANITARIYA. FOR ENGLISH TRANSLATION, SE E HYSAAV. 38(5), 11. IPR;
GPG; LD50: 13 MG/KG 1973. GIGIENA I SANITARIYA. FOR ENGLISH
TRANSLATION, SEE HYSAAV. 38(5), 11. IVN; MUS; LD50: 6 MG/KG 1980.
'CRC HANDBOOK OF ANTIBIOTIC COMPOUNDS.' 1,202. ( ECOLOGICAL INFO)

Disclaimer (provided with this information by the compiling agencies):
This information is formulated for use by elements of the Department
of Defense. The United States of America in no manner whatsoever,
expressly or implied, warrants this information to be accurate and
disclaims all liability for its use. Any person utilizing this
document should seek competent professional advice to verify and
assume responsibility for the suitability of this information to their
particular situation.

Ecological:NO INFORMATION AVAILABLE. --TOXICOLOGICAL INFO: REFER TO THE
REGISTRY OF TOXIC EFFECTS OF CHEMICAL SUBSTANCES (RTECS) FOR A
DEFINITION OF ABBREVIATIONS USED IN THE ABOVE TEXT AND FOR
ADDITIONAL INFORM ATION. THIS REPORT CONTAINS ONLY SELECTED
INFORMATION FROM THE RTECS.

Transport Information:UN NUMBER: UN2810. PROPER SHIPPING NAME: TOXIC
LIQUID, ORGANIC, N.O.S. IATA CLASS: 6.1. IATA PACKING GROUP: III.

Federal Regulatory Information:REGULATORY INFORMATION: T+; XI. RISK
PHRASES: R26/27/28: VERY TOXIC BY INHALATION, IN CONTACT WITH SKIN
AND IF SWALLOWED. R37/38: IRRITATING TO RESPIRATORY SYSTEM AND
SKIN. R41; RISK OF SERIOUS DAMAGE TO EYES. R48: DANGER OF SERIOUS
DAMAGE TO HEALTH BY PROLONGED EXPOSURE. SAFETY PHRASES: S24/25:
AVOID CONTCT WITH SKIN AND EYES. S26: IN CASE OF CONTACT WITH EYES,
RINSE IMMEDIATELY WITH PLENTY OF WA TER AND SEEK MEDICAL ADVICE.
S36/37/39: WEAR SUITABLE PROTECTIVE CLOTHING, GLOVES AND EYE/FACE
PROTE CTION. S45: IN CASE OF ACCIDENT OR IF YOU FEEL UNWELL, SEEK
MEDICAL ADVICE IMMEDIATELY.